FDA warns of birth defects with Topamax

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WASHINGTON (AP) — The Food and Drug Administration is warning women of child-bearing age that the epilepsy drug Topamax can increase the risk of birth defects around the mouth.

Regulators said Friday that data collected from a registry of pregnant women showed a higher rate of cleft lip and cleft palate in babies whose mothers were taking the drug during the first trimester. Infants who were exposed to the drug had a 1.4 percent rate of mouth defects, which was more

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