Boris Johnson has accused MPs “who think they can block Brexit” of a “terrible collaboration” with the European Union.
The prime minister said the EU had become less willing to compromise on a new deal with the UK because of the opposition to leaving in Parliament.
He said this increased the likelihood of the UK being “forced to leave with a no-deal” in October.
The EU has said the agreement struck by Theresa May is the only deal possible.
Speaking during a Facebook event hosted at Downing Street, Mr Johnson said he wanted to leave with a deal but “we need our European friends to compromise”.
“There’s a terrible kind of collaboration as it were, going on between people who think they can block Brexit in Parliament