Biogen had announced in March that it would terminate two large clinical trials of aducanumab because they were likely to fail [File: Yves Herman/Reuters]

United States biotechnology company Biogen Inc’s shock decision this week to bring its experimental Alzheimer’s drug back from the scrap heap was born out of “top secret” meetings, non-disclosure agreements and six months of hashing over trial data with scientists, regulators and statisticians, researchers told Reuters.

Biogen had announced in March that it would terminate two large clinical trials of aducanumab because they were likely to fail. Within weeks, a group of company researchers set out to understand what went wrong.

As they studied data from a larger pool of patients who received the drug, they began to question

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