Disabled employees are paid 12.2% less than their non-disabled peers, according to official data.
The Office for National Statistics (ONS) found that in 2018 the median pay for non-disabled workers was £12.11 an hour, against £10.63 for disabled.
London had the widest disability pay gap at 15.3%, with the narrowest in Scotland, at 8.3%.
The gap was the widest for those in their 30s and 40s, the ONS said in its report.
The data underlines the struggle facing many disabled workers, the Chartered Institute of Personnel and Development (CIPD) said.
“Too many disabled people continue to face prejudice and struggle to get into employment or to remain in work, and are less likely to progress to senior management roles or to work in professional occupations,” said the CIPD’s Dr Jill