An early life full of neglect, deprivation and adversity leads to people growing up with smaller brains, a study suggests.

The researchers at King’s College London were following adopted children who spent time in “hellhole” Romanian orphanages.

They grew up with brains 8.6% smaller than other adoptees.

The researchers said it was the “first and most compelling” evidence of the impact on the developing brain.

The appalling care at the orphanages came to light after the fall of Romania’s communist dictator Nicolae Ceausescu in 1989.

“I remember TV pictures of those institutions, they were shocking,” Prof Edmund Sonuga-Barke, who now leads the study following those children, told the BBC.

He described the institutions as “hellholes” where children were “chained into their cots, rocking, filthy and emaciated”.

The children were

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