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NHS England has urged Instagram to clamp down on accounts selling an unlicensed, “dangerous” drug mainly targeted at younger women and girls.

The sale of Apetamin is illegal in the UK, but BBC Three revealed it is available in shops and online.

In an open letter, NHS leaders say they are concerned about the product’s promotion and the impact on physical and mental health.

Instagram say selling non-medical drugs is “strictly against our policies”.

Apetamin is not licensed in the UK which means the regulator has not carried out tests to ensure it meets strict safety standards and

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