More severe COVID-19 may raise risk of long COVID – CIDRAP

by | Oct 31, 2022 | COVID-19

A large study released today suggests that people who experience worse COVID-19 symptoms may be more likely to subsequently develop notable symptoms 12 weeks or more after the initial infection. Also, most patients went on to have long COVID, regardless of the severity of their original illness.The study, published by the European Centre for Disease Prevention and Control (ECDC), was based on data collected on pre-Omicron infections. A total of 61 cohort studies from 15 countries were included in the analysis, which included 74,213 post–COVID-19 cases that had been assessed at least 12 weeks after infection in the European Union (EU)/European Economic Area (EEA), the United Kingdom, United States, Canada, Australia, and New Zealand.The systematic review and meta-analysis estimated the prevalence of symptoms of post COVID-19 condition, stratified by recruitment setting (community, hospital, and intensive care unit [ICU]) as a proxy for disease severity.Five post–COVID-19 symptoms—fatigue, shortness of breath, depression, headache, and dizziness—were noted to be more prevalent in patients from hospital settings than community settings, suggesting that severity of disease is a factor in determining who is at risk for developing long COVID.Long COVID in 51% to 74% of patientsOverall, the authors found very high rates of post-COVID symptoms: The prevalence of any post–COVID-19 condition symptom was estimated at 50.6% (95% confidence interval [CI], 41.1% to 60.2%) among cohorts recruited in the community setting; 66.5% (9 …

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