Next Avenue: What neuroscientists have learned about rejuvenating the aging brain—and what you can do too

by | Nov 2, 2022 | Stock Market

This article is reprinted by permission from We all understand that no magic elixir can stop or even slow the human brain or skeletal muscles from aging. But is that true? After two decades of research with mice, Tony Wyss-Coray, Ph.D., a neuroscientist at Stanford University, has some ideas about what might work. Follow-up trials with humans have indeed demonstrated the possibilities.

What the research says According to Wyss-Coray, quoted in Stanford University’s School of Medicine newsletter, Scope, “when we treated old mice with repeated intravenous infusions of young plasma (the liquid fraction of blood), these mice became smarter, performing more like young mice on multiple cognitive tests. Conversely, young mice exposed to aged blood or treated with aged plasma experienced accelerated aging of the brain and a loss of cognitive function.”  That means that, at least in the lab, for now, some techniques that rejuvenate blood may hold promise for improving the performance of the aging human brain in the future. In another recent study, “among all U.S. adults, an estimated 41.0% of dementia cases were attributable to 12 risk factors…” including hypertension, obesity, and physical inactivity. So any new activities stimulating the mind or body help ward off decline and maybe even dementia. This is encouraging. Bruce Goldman, a writer for Stanford University’s School of Medicine newsletter, reported that the losses in cognitive functioning that begin in midlife, between age 50 and 60, may not be inevitable.  And while the typical difficulties with word retrieval that many older adults have seem just annoying to beg …

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